Peptide quality control typically combines analytical methods that confirm identity, purity, and consistency before a product is released for laboratory use.
Common QC methods
- Reverse-phase HPLC: Assesses purity by separating the target peptide from related impurities, truncations, and synthesis byproducts.
- Mass spectrometry (MS): Verifies the expected molecular weight and helps confirm the peptide sequence or composition.
- Certificate of Analysis (COA): Summarizes test results, batch identifiers, and acceptance criteria for a specific lot.
Additional checks may include appearance, packaging integrity, and documentation review to support lot traceability and handling control. For purchasing teams, it is useful to confirm that QC data are tied to the exact batch received and that methods are clearly stated rather than implied.
Research peptides should be labeled and supplied for laboratory research use only and are not intended for human consumption.