To read a peptide COA, start by matching the product name, lot number, and date to the material you received. These identifiers should be consistent across the COA, vial label, and packing documents.
Key sections to review
- Identity: Confirms the peptide sequence or stated compound name, often supported by mass spectrometry data.
- Purity: Usually reported as a percentage from HPLC analysis. Review the chromatogram if provided, not just the summary value.
- Method details: Check the analytical method, such as HPLC conditions or MS instrument type, because test methods affect interpretation.
- Impurities or related substances: Note any listed secondary peaks, degradation products, or unspecified impurities.
- Storage conditions: Verify any handling or temperature guidance relevant to maintaining sample integrity.
For research purchasing, a COA should be internally consistent, legible, and specific to the batch in hand. If critical data are missing, request clarification from the supplier before use. Products should be intended for research use only and not for human consumption.